Aminopeptidase secreted by Chromobacterium sp. Panama inhibits dengue virus infection by degrading the E protein.

• Main Authors: Raúl G Saraiva (Author), Jingru Fang (Author), Seokyoung Kang (Author), Yesseinia I Angleró-Rodríguez (Author), Yuemei Dong (Author), George Dimopoulos (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2018-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Dengue virus (DENV) is the most prevalent and burdensome arbovirus transmitted by Aedes mosquitoes, against which there is only a limited licensed vaccine and no approved drug treatment. A Chromobacterium species, C. sp. Panama, isolated from the midgut of A. aegypti is able to inhibit DENV replicat...