An integrated genomic profile that includes copy number alterations is highly predictive of minimal residual disease status in childhood precursor B-lineage acute lymphoblastic leukemia

• Main Authors: Nikhil Patkar (Author), P G Subramanian (Author), Prashant Tembhare (Author), Sneha Mandalia (Author), Gaurav Chaterjee (Author), Nikhil Rabade (Author), Rohan Kodgule (Author), Karishma Chopra (Author), Asma Bibi (Author), Swapnali Joshi (Author), Shruti Chaudhary (Author), Russel Mascerhenas (Author), Pratibha Kadam-Amare (Author), Gaurav Narula (Author), Brijesh Arora (Author), Shripad Banavali (Author), Sumeet Gujral (Author)
• Format: Book
• Published: Wolters Kluwer Medknow Publications, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Copy number alterations (CNA) have been described in childhood precursor B-lineage acute lymphoblastic leukemia (B-ALL) which in conjunction with chromosomal abnormalities drive leukemogenesis. There is no consensus on the clinical incorporation of CNA in B-ALL. An integrated genomic c...