Iguratimod Attenuates Macrophage Polarization and Antibody-Mediated Rejection After Renal Transplant by Regulating KLF4

• Main Authors: Zhou Hang (Author), Jintao Wei (Author), Ming Zheng (Author), Zeping Gui (Author), Hao Chen (Author), Li Sun (Author), Shuang Fei (Author), Zhijian Han (Author), Jun Tao (Author), Zijie Wang (Author), Ruoyun Tan (Author), Min Gu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: This study aimed to explore the effect and mechanism of iguratimod (IGT) on M1 macrophage polarization and antibody-mediated rejection (ABMR) after renal transplant.Methods: Bioinformatics analysis was performed using three public databases derived from the GEO database. Sprague-Dawley (...