Infiltrating treg reprogramming in the tumor immune microenvironment and its optimization for immunotherapy

• Main Authors: Zhaokai Zhou (Author), Jiaxin Xu (Author), Shutong Liu (Author), Yingying Lv (Author), Ruiqi Zhang (Author), Xing Zhou (Author), Yuyuan Zhang (Author), Siyuan Weng (Author), Hui Xu (Author), Yuhao Ba (Author), Anning Zuo (Author), Xinwei Han (Author), Zaoqu Liu (Author)
• Format: Book
• Published: BMC, 2024-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Immunotherapy has shown promising anti-tumor effects across various tumors, yet it encounters challenges from the inhibitory tumor immune microenvironment (TIME). Infiltrating regulatory T cells (Tregs) are important contributors to immunosuppressive TIME, limiting tumor immunosurveillance...