Bezafibrate Exerts Neuroprotective Effects in a Rat Model of Sporadic Alzheimer's Disease

• Main Authors: Li-Fan Lin (Author), Yun-Ting Jhao (Author), Chuang-Hsin Chiu (Author), Lu-Han Sun (Author), Ta-Kai Chou (Author), Chyng-Yann Shiue (Author), Cheng-Yi Cheng (Author), Kuo-Hsing Ma (Author)
• Format: Book
• Published: MDPI AG, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Bezafibrate, a pan-peroxisome proliferator-activated receptor (PPAR) agonist, reportedly attenuated tau pathology in a transgenic mouse model of primary tauopathy. Since tau pathology is a neuropathological hallmark of Alzheimer's disease (AD), bezafibrate may be a potential drug for the treatm...