The influence of drug-induced metabolic enzyme activity inhibition and CYP3A4 gene polymorphism on aumolertinib metabolism
The purpose of this study is to clarify the drug interaction profile of aumolertinib, and the influence of CYP3A4 genetic polymorphism on aumolertinib metabolic characteristics. Through microsomal enzyme reactions, we screened 153 drugs and identified 15 that significantly inhibited the metabolism o...
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| Main Authors: | , , , , , , , , , |
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| Format: | Book |
| Published: |
Frontiers Media S.A.,
2024-05-01T00:00:00Z.
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