Oxyresveratrol Inhibits TNF-α-Stimulated Cell Proliferation in Human Immortalized Keratinocytes (HaCaT) by Suppressing AKT Activation

Oxyresveratrol Inhibits TNF-α-Stimulated Cell Proliferation in Human Immortalized Keratinocytes (HaCaT) by Suppressing AKT Activation

Psoriasis is a complex inflammatory disease characterized by hyperproliferative keratinocyte caused by active PI3K/AKT signaling. TNF-α concentrated in the psoriatic lesions stimulates AKT activation. We previously discovered that oxyresveratrol inhibited inflammation via suppressing AKT phosphoryla...

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Main Authors: Nitwara Wikan (Author), Phateep Hankittichai (Author), Phatarawat Thaklaewphan (Author), Saranyapin Potikanond (Author), Wutigri Nimlamool (Author)
Format: Book
Published: MDPI AG, 2021-12-01T00:00:00Z.
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