Boronic acid inhibitors of penicillin-binding protein 1b: serine and lysine labelling agents

Boronic acid inhibitors of penicillin-binding protein 1b: serine and lysine labelling agents

AbstractPenicillin-binding proteins (PBPs) contribute to bacterial cell wall biosynthesis and are targets of antibacterial agents. Here, we investigated PBP1b inhibition by boronic acid derivatives. Chemical starting points were identified by structure-based virtual screening and aliphatic boronic a...

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Main Authors: Levente Kollár (Author), Katarina Grabrijan (Author), Martina Hrast Rambaher (Author), Krištof Bozovičar (Author), Tímea Imre (Author), György G. Ferenczy (Author), Stanislav Gobec (Author), György M. Keserű (Author)
Format: Book
Published: Taylor & Francis Group, 2024-12-01T00:00:00Z.
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