Boronic acid inhibitors of penicillin-binding protein 1b: serine and lysine labelling agents
AbstractPenicillin-binding proteins (PBPs) contribute to bacterial cell wall biosynthesis and are targets of antibacterial agents. Here, we investigated PBP1b inhibition by boronic acid derivatives. Chemical starting points were identified by structure-based virtual screening and aliphatic boronic a...
Saved in:
| Main Authors: | Levente Kollár (Author), Katarina Grabrijan (Author), Martina Hrast Rambaher (Author), Krištof Bozovičar (Author), Tímea Imre (Author), György G. Ferenczy (Author), Stanislav Gobec (Author), György M. Keserű (Author) |
|---|---|
| Format: | Book |
| Published: |
Taylor & Francis Group,
2024-12-01T00:00:00Z.
|
| Subjects: | |
| Online Access: | Connect to this object online. |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Next-Generation Heterocyclic Electrophiles as Small-Molecule Covalent MurA Inhibitors
by: Péter Ábrányi-Balogh, et al.
Published: (2022) -
Bromo-Cyclobutenaminones as New Covalent UDP-<i>N</i>-Acetylglucosamine Enolpyruvyl Transferase (MurA) Inhibitors
by: David J. Hamilton, et al.
Published: (2020) -
The Impact of the Secondary Binding Pocket on the Pharmacology of Class A GPCRs
by: Attila Egyed, et al.
Published: (2022) -
Glycosyltransferases and Transpeptidases/Penicillin-Binding Proteins: Valuable Targets for New Antibacterials
by: Eric Sauvage, et al.
Published: (2016) -
The Boron Advantage: The Evolution and Diversification of Boron's Applications in Medicinal Chemistry
by: Katia Messner, et al.
Published: (2022)