The reliability and integrity of overall survival data based on follow-up records only and potential solutions to the challenges

• Main Authors: Huiyao Huang (Author), Yu Tang (Author), Yue Yu (Author), Anqi Yu (Author), Dawei Wu (Author), Hong Fang (Author), Shuhang Wang (Author), Chao Sun (Author), Xin Wang (Author), Qi Fan (Author), Yuan Fang (Author), Qiyu Tang (Author), Ning Jiang (Author), Jingting Du (Author), Huilei Miao (Author), Ying Bai (Author), Peiwen Ma (Author), Shujun Xing (Author), Dandan Cui (Author), Shuangman Miao (Author), Yale Jiang (Author), Jingxiao Zhu (Author), Qi Zhu (Author), Ye Leng (Author), Lan Wei Guo (Author), Shanmei Liao (Author), Yaguang Shao (Author), Yinyin Song (Author), Zeyuan Liu (Author), Minghuang Hong (Author), Suxia Luo (Author), Binghe Xu (Author), Gongtao Lan (Author), Ning Li (Author)
• Format: Book
• Published: Elsevier, 2023-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Summary: Overall survival (OS) is considered the standard clinical endpoint to support effectiveness claims in new drug applications globally, particularly for lethal conditions such as cancer. However, the source and reliability of OS in the setting of clinical trials have seldom been doubted and d...