Pyridoxal-5'-Phosphate Promotes Immunomodulatory Function of Adipose-Derived Mesenchymal Stem Cells through Indoleamine 2,3-Dioxygenase-1 and TLR4/NF-κB Pathway

• Główni autorzy: Cong Li (Autor), Jinxian Huang (Autor), Huasu Zhu (Autor), Qing Shi (Autor), Dong Li (Autor), Xiuli Ju (Autor)
• Format: Książka
• Wydane: Hindawi Limited, 2019-01-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Adipose-derived mesenchymal stem cells (A-MSCs) are promising cellular therapies for the treatment of immune-mediated diseases. Non-gene editing technologies can improve the immune regulatory function of A-MSCs. Our preliminary experiments revealed that an active form of vitamin B6-pyridoxal-5'...