Identification of MYOM2 as a candidate gene in hypertrophic cardiomyopathy and Tetralogy of Fallot, and its functional evaluation in the Drosophila heart

• Glavni autori: Emilie Auxerre-Plantié (Autor), Tanja Nielsen (Autor), Marcel Grunert (Autor), Olga Olejniczak (Autor), Andreas Perrot (Autor), Cemil Özcelik (Autor), Dennis Harries (Autor), Faramarz Matinmehr (Autor), Cristobal Dos Remedios (Autor), Christian Mühlfeld (Autor), Theresia Kraft (Autor), Rolf Bodmer (Autor), Georg Vogler (Autor), Silke R. Sperling (Autor)
• Format: Knjiga
• Izdano: The Company of Biologists, 2020-12-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

The causal genetic underpinnings of congenital heart diseases, which are often complex and multigenic, are still far from understood. Moreover, there are also predominantly monogenic heart defects, such as cardiomyopathies, with known disease genes for the majority of cases. In this study, we identi...