High rate of subclinical chikungunya virus infection and association of neutralizing antibody with protection in a prospective cohort in the Philippines.

• Main Authors: In-Kyu Yoon (Author), Maria Theresa Alera (Author), Catherine B Lago (Author), Ilya A Tac-An (Author), Daisy Villa (Author), Stefan Fernandez (Author), Butsaya Thaisomboonsuk (Author), Chonticha Klungthong (Author), Jens W Levy (Author), John Mark Velasco (Author), Vito G Roque (Author), Henrik Salje (Author), Louis R Macareo (Author), Laura L Hermann (Author), Ananda Nisalak (Author), Anon Srikiatkhachorn (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2015-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND:Chikungunya virus (CHIKV) is a globally re-emerging arbovirus for which previous studies have indicated the majority of infections result in symptomatic febrile illness. We sought to characterize the proportion of subclinical and symptomatic CHIKV infections in a prospective cohort study...