Berberine Inhibits Nod-Like Receptor Family Pyrin Domain Containing 3 Inflammasome Activation and Pyroptosis in Nonalcoholic Steatohepatitis via the ROS/TXNIP Axis

• Main Authors: Weijian Mai (Author), Yangzhi Xu (Author), Jiahui Xu (Author), Dan Zhao (Author), Liangying Ye (Author), Ganxiang Yu (Author), Zhilei Wang (Author), Qianting Lu (Author), Jiaen Lin (Author), Tao Yang (Author), Chengxin Gu (Author), Shiming Liu (Author), Yun Zhong (Author), Hui Yang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Berberine (BBR), an isoquinoline alkaloid originating from herbal plants, has been deemed beneficial for non-alcoholic fatty liver disease. Increasing evidence has demonstrated that Nod-like receptor family pyrin domain containing 3 (NLRP3) inflammasome activation and the subsequent pyroptosis contr...