The Major Role of NF-κB in the Depth of Invasion on Acral Melanoma by Decreasing CD8 T Cells

• मुख्य लेखकों: Hermin Aminah Usman (लेखक), Bethy S. Hernowo (लेखक), Maringan Diapari Lumban Tobing (लेखक), Reti Hindritiani (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Korean Society of Pathologists & the Korean Society for Cytopathology, 2018-05-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Background The tumor microenvironment including immune surveillance affects malignant melanoma (MM) behavior. Nuclear factor κB (NF-κB) stimulates the transcription of various genes in the nucleus and plays a role in the inflammatory process and in tumorigenesis. CD8+ T cells have cytotoxic properti...