Heterozygous COL4A3 Variants in Histologically Diagnosed Focal Segmental Glomerulosclerosis

• Main Authors: Matthias C. Braunisch (Author), Maike Büttner-Herold (Author), Roman Günthner (Author), Robin Satanovskij (Author), Korbinian M. Riedhammer (Author), Pierre-Maurice Herr (Author), Hanns-Georg Klein (Author), Dagmar Wahl (Author), Claudius Küchle (Author), Lutz Renders (Author), Uwe Heemann (Author), Christoph Schmaderer (Author), Julia Hoefele (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Steroid-resistant nephrotic syndrome (SRNS) is one of the most frequent causes for chronic kidney disease in childhood. In ~30% of these cases a genetic cause can be identified. The histological finding in SRNS is often focal segmental glomerulosclerosis (FSGS). In rare cases, however,...