Adiponectin restores the obesity-induced impaired immunomodulatory function of mesenchymal stromal cells via glycolytic reprogramming

• Main Authors: Duc-Vinh Pham (Author), Thi-Kem Nguyen (Author), Bao-Loc Nguyen (Author), Jong-Oh Kim (Author), Jee-Heon Jeong (Author), Inho Choi (Author), Pil-Hoon Park (Author)
• Format: Book
• Published: Elsevier, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Obesity has been known to negatively modulate the life-span and immunosuppressive potential of mesenchymal stromal cells (MSC). However, it remains unclear what drives the compromised potency of obese MSC. In this study, we examined the involvement of adiponectin, an adipose tissue-derived hormone,...