Synthesis and Preliminary Evaluation of a 2-Oxoquinoline Carboxylic Acid Derivative for PET Imaging the Cannabinoid Type 2 Receptor

• Prif Awduron: Linjing Mu (Awdur), Roger Slavik (Awdur), Adrienne Müller (Awdur), Kasim Popaj (Awdur), Stjepko Čermak (Awdur), Markus Weber (Awdur), Roger Schibli (Awdur), Stefanie D. Krämer (Awdur), Simon M. Ametamey (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: MDPI AG, 2014-03-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

Cannabinoid receptor subtype 2 (CB2) has been shown to be up-regulated in activated microglia and therefore plays an important role in neuroinflammatory and neurodegenerative diseases such as multiple sclerosis, amyotrophic lateral sclerosis and Alzheimer's disease. The CB2 receptor is therefor...