Pharmacokinetics and biodistribution of a novel anticancer thyrointegrin αvβ3 antagonist: triazole modified tetraiodothyroacetic acid conjugated to polyethylene glycol (P-bi-TAT)

Abstract We previously developed a triazole modified tetraiodothyroacetic acid (TAT) conjugated to a polyethylene glycol (PEG)-based thyrointegrin αvβ3 antagonist targeted compound, called P-bi-TAT. It exhibited potent anti-angiogenic and anticancer activities in vivo. The objective of the current s...

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Päätekijät: Kazutoshi Fujioka (Tekijä), Kavitha Godugu (Tekijä), Shaker A. Mousa (Tekijä)
Aineistotyyppi: Kirja
Julkaistu: SpringerOpen, 2021-08-01T00:00:00Z.
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