Bactericidal antibodies against hypervirulent Neisseria meningitidis C field strains following MenC-CRM or MenACWY-CRM priming and MenACWY-CRM booster in children

• Main Authors: Marzia Monica Giuliani (Author), Alessia Biolchi (Author), Pavitra Keshavan (Author), Maria Moriondo (Author), Sara Tomei (Author), Laura Santini (Author), Elena Mori (Author), Alessandro Brozzi (Author), Margherita Bodini (Author), Francesco Nieddu (Author), Silvia Ricci (Author), Thembile Mzolo (Author), Marco Costantini (Author), Chiara Azzari (Author), Michele Pellegrini (Author)
• Format: Book
• Published: Taylor & Francis Group, 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

An increase in invasive meningococcal disease (IMD) incidence was observed in Tuscany in 2015/2016, mainly due to hypervirulent clonal complex (cc) 11 strains. In a post-hoc analysis, we assessed bactericidal activity of antibodies in sera from children primed with MenACWY-CRM or MenC-CRM conjugate...