Schistosoma mansoni Infection Can Jeopardize the Duration of Protective Levels of Antibody Responses to Immunizations against Hepatitis B and Tetanus Toxoid.

• Main Authors: Diana K Riner (Author), Eric M Ndombi (Author), Jennifer M Carter (Author), Amos Omondi (Author), Nupur Kittur (Author), Emmy Kavere (Author), Harrison K Korir (Author), Briana Flaherty (Author), Diana Karanja (Author), Daniel G Colley (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2016-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Schistosomiasis is a disease of major public health importance in sub-Saharan Africa. Immunoregulation begins early in schistosome infection and is characterized by hyporesponsiveness to parasite and bystander antigens, suggesting that a schistosome infection at the time of immunization could negati...