Carboplatin: molecular mechanisms of action associated with chemoresistance

• मुख्य लेखकों: Graziele Fonseca de Sousa (लेखक), Samarina Rodrigues Wlodarczyk (लेखक), Gisele Monteiro (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Universidade de São Paulo, 2014-12-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Carboplatin is a derivative of cisplatin; it has a similar mechanism of action, but differs in terms of structure and toxicity. It was approved by the FDA in the 1980s and since then it has been widely used in the treatment of several tumor types. This agent is characterized by its ability to genera...