Carboplatin: molecular mechanisms of action associated with chemoresistance

• Главные авторы: Graziele Fonseca de Sousa (Автор), Samarina Rodrigues Wlodarczyk (Автор), Gisele Monteiro (Автор)
• Формат: ‌
• Опубликовано: Universidade de São Paulo, 2014-12-01T00:00:00Z.
• Предметы: article
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Carboplatin is a derivative of cisplatin; it has a similar mechanism of action, but differs in terms of structure and toxicity. It was approved by the FDA in the 1980s and since then it has been widely used in the treatment of several tumor types. This agent is characterized by its ability to genera...