Paneth cell ablation in the presence of Klebsiella pneumoniae induces necrotizing enterocolitis (NEC)-like injury in the small intestine of immature mice

SUMMARY Necrotizing enterocolitis (NEC) is a leading cause of morbidity and mortality in premature infants. During NEC pathogenesis, bacteria are able to penetrate innate immune defenses and invade the intestinal epithelial layer, causing subsequent inflammation and tissue necrosis. Normally, Paneth...

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Main Authors: Chunxian Zhang (Author), Michael P. Sherman (Author), Lawrence S. Prince (Author), David Bader (Author), Jörn-Hendrik Weitkamp (Author), James C. Slaughter (Author), Steven J. McElroy (Author)
Format: Book
Published: The Company of Biologists, 2012-07-01T00:00:00Z.
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