Autoinducer Analogs Can Provide Bactericidal Activity to Macrolides in <i>Pseudomonas aeruginosa</i> through Antibiotic Tolerance Reduction

• Main Authors: Mizuki Abe (Author), Keiji Murakami (Author), Yuka Hiroshima (Author), Takashi Amoh (Author), Mayu Sebe (Author), Keiko Kataoka (Author), Hideki Fujii (Author)
• Format: Book
• Published: MDPI AG, 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Macrolide antibiotics are used in treating <i>Pseudomonas aeruginosa</i> chronic biofilm infections despite their unsatisfactory antibacterial activity, because they display several special activities, such as modulation of the bacterial quorum sensing and immunomodulatory effects on the...