Lymphotoxin-α Plays Only a Minor Role in Host Resistance to Respiratory Infection with Virulent Type A Francisella tularensis in Mice

• Auteurs principaux: Deng Zhang (Auteur), Rhonda KuoLee (Auteur), Greg Harris (Auteur), Qinxian Zhang (Auteur), J. Wayne Conlan (Auteur), Wangxue Chen (Auteur)
• Format: Livre
• Publié: Hindawi Limited, 2008-01-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

This study examined the role of lymphotoxin (LT)-α in host defense against airborne infection with Francisella tularensis, a gram-negative facultative intracellular bacterium and the causative agent of tularemia. Following a low-dose aerosol infection with the highly virulent type A strain of F. tul...