Hesperidin activates Nrf2 to protect cochlear hair cells from cisplatin-induced damage

• Main Authors: Jintao Lou (Author), Fan Wu (Author), Wuhui He (Author), Rui Hu (Author), Ziyi Cai (Author), Guisheng Chen (Author), Wenji Zhao (Author), Zhigang Zhang (Author), Yu Si (Author)
• Format: Book
• Published: Taylor & Francis Group, 2024-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

ABSTRACTCisplatin is widely employed in clinical oncology as an anticancer chemotherapy drug in clinical practice and is known for its severe ototoxic side effects. Prior research indicates that the accumulation of reactive oxygen species (ROS) plays a pivotal role in cisplatin's inner ear toxi...