NPC1161B, an 8-Aminoquinoline Analog, Is Metabolized in the Mosquito and Inhibits Plasmodium falciparum Oocyst Maturation

• Главные авторы: Timothy Hamerly (Автор), Rebecca E. Tweedell (Автор), Bernadette Hritzo (Автор), Vincent O. Nyasembe (Автор), Babu L. Tekwani (Автор), N. P. Dhammika Nanayakkara (Автор), Larry A. Walker (Автор), Rhoel R. Dinglasan (Автор)
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• Опубликовано: Frontiers Media S.A., 2019-10-01T00:00:00Z.
• Предметы: article
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Malaria is a major global health threat, with nearly half the world's population at risk of infection. Given the recently described delayed clearance of parasites by artemisinin-combined therapies, new antimalarials are needed to facilitate the global effort toward elimination and eradication....