CD8+ T lymphocyte expansion, proliferation and activation in dengue fever.

• Main Authors: Andréia Manso de Matos (Author), Karina Inacio Carvalho (Author), Daniela Santoro Rosa (Author), Lucy Santos Villas-Boas (Author), Wanessa Cardoso da Silva (Author), Célia Luiza de Lima Rodrigues (Author), Olímpia Massae Nakasone Peel Furtado Oliveira (Author), José Eduardo Levi (Author), Evaldo Stanislau Affonso Araújo (Author), Claudio Sergio Pannuti (Author), Expedito José Albuquerque Luna (Author), Esper George Kallas (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2015-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Dengue fever induces a robust immune response, including massive T cell activation. The level of T cell activation may, however, be associated with more severe disease. In this study, we explored the level of CD8+ T lymphocyte activation in the first six days after onset of symptoms during a DENV2 o...