A functional variant alters binding of activating protein 1 regulating expression of FGF7 gene associated with chronic obstructive pulmonary disease

• Autors principals: Xiaomei Zhang (Autor), Yongxin Guo (Autor), Jing Yang (Autor), Jianlou Niu (Autor), Lina Du (Autor), Haiyan Li (Autor), Xiaokun Li (Autor)
• Format: Llibre
• Publicat: BMC, 2019-02-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Abstract Background Genome-wide association studies (GWASs) of a large cohort of subjects with chronic obstructive pulmonary disease (COPD) have successfully identified multiple risk genes, including fibroblast growth factor 7 (FGF7). However, the underlying molecular mechanism influencing function...