Relative bioavailability of a pediatric dispersible tablet and adult film‐coated tablet of macitentan in healthy volunteers

• Egile Nagusiak: Patricia N. Sidharta (Egilea), Radka Štěpánová (Egilea), Susanne Globig (Egilea), Ivan Ulč (Egilea), Dénes Csonka (Egilea)
• Formatua: Liburua
• Argitaratua: Wiley, 2020-04-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Abstract To compare the pharmacokinetic (PK) properties of the pediatric dispersible tablet formulation of macitentan and the adult film‐coated tablet formulation of macitentan in healthy subjects. A randomized, open‐label, single‐dose, two‐sequence, two‐period, crossover, Phase 1 study was conducte...