Research Models to Study Ferroptosis's Impact in Neurodegenerative Diseases

• Main Authors: Inês Costa (Author), Daniel José Barbosa (Author), Vera Silva (Author), Sofia Benfeito (Author), Fernanda Borges (Author), Fernando Remião (Author), Renata Silva (Author)
• Format: Book
• Published: MDPI AG, 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Ferroptosis is a type of regulated cell death promoted by the appearance of oxidative perturbations in the intracellular microenvironment constitutively controlled by glutathione peroxidase 4 (GPX4). It is characterized by increased production of reactive oxygen species, intracellular iron accumulat...