Polypeptide Self-Assembled Nanoparticles as Delivery Systems for Polymyxins B and E

• Hoofdauteurs: Dmitrii Iudin (Auteur), Natalia Zashikhina (Auteur), Elena Demyanova (Auteur), Viktor Korzhikov-Vlakh (Auteur), Elena Shcherbakova (Auteur), Roman Boroznjak (Auteur), Irina Tarasenko (Auteur), Natalya Zakharova (Auteur), Antonina Lavrentieva (Auteur), Yury Skorik (Auteur), Evgenia Korzhikova-Vlakh (Auteur)
• Formaat: Boek
• Gepubliceerd in: MDPI AG, 2020-09-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Polymyxins are peptide antibiotics that are highly efficient against many multidrug resistant pathogens. However, the poor stability of polymyxins in the bloodstream requires the administration of high drug doses that, in turn, can lead to polymyxin toxicity. Consequently, different delivery systems...