Comparison of sGC activator and sGC stimulator in 5/6 nephrectomized rats on high-salt-diet

• Main Authors: Xin Chen (Author), Yingquan Xiong (Author), Shufei Zeng (Author), Denis Delić (Author), Mohamed Gaballa (Author), Philipp Kalk (Author), Thomas Klein (Author), Bernhard K. Krämer (Author), Berthold Hocher (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

IntroductionSoluble guanylate cyclase (sGC) stimulators and activators are known to enhance kidney function in various models of chronic kidney disease (CKD) by increasing cyclic guanosine monophosphate (cGMP). Their differential effects on CKD progression, particularly under conditions of oxidative...