Terrein suppressed lipopolysaccharide-induced neuroinflammation through inhibition of NF-κB pathway by activating Nrf2/HO-1 signaling in BV2 and primary microglial cells

In the course of our continuous investigation on the bioactive marine-derived fungal metabolites, terrein was isolated from marine-derived fungal strain Penicillium sp. SF-7181. Terrein inhibited the overproduction of pro-inflammatory mediators, such as nitric oxide (NO) and prostaglandin E2 (PGE2),...

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Main Authors: Kwan-Woo Kim (Author), Hye Jin Kim (Author), Jae Hak Sohn (Author), Joung Han Yim (Author), Youn-Chul Kim (Author), Hyuncheol Oh (Author)
Format: Book
Published: Elsevier, 2020-07-01T00:00:00Z.
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