Terrein suppressed lipopolysaccharide-induced neuroinflammation through inhibition of NF-κB pathway by activating Nrf2/HO-1 signaling in BV2 and primary microglial cells
In the course of our continuous investigation on the bioactive marine-derived fungal metabolites, terrein was isolated from marine-derived fungal strain Penicillium sp. SF-7181. Terrein inhibited the overproduction of pro-inflammatory mediators, such as nitric oxide (NO) and prostaglandin E2 (PGE2),...
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Main Authors: | Kwan-Woo Kim (Author), Hye Jin Kim (Author), Jae Hak Sohn (Author), Joung Han Yim (Author), Youn-Chul Kim (Author), Hyuncheol Oh (Author) |
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Format: | Book |
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Elsevier,
2020-07-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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