The Role of Antioxidants in the Interplay between Oxidative Stress and Senescence

• Main Authors: Angelica Varesi (Author), Salvatore Chirumbolo (Author), Lucrezia Irene Maria Campagnoli (Author), Elisa Pierella (Author), Gaia Bavestrello Piccini (Author), Adelaide Carrara (Author), Giovanni Ricevuti (Author), Catia Scassellati (Author), Cristian Bonvicini (Author), Alessia Pascale (Author)
• Format: Book
• Published: MDPI AG, 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cellular senescence is an irreversible state of cell cycle arrest occurring in response to stressful stimuli, such as telomere attrition, DNA damage, reactive oxygen species, and oncogenic proteins. Although beneficial and protective in several physiological processes, an excessive senescent cell bu...