Copy number variation profile in noninvasive prenatal testing (NIPT) can identify co-existing maternal malignancies: Case reports and a literature review

• Main Authors: Xing Ji (Author), Fang Chen (Author), Yafeng Zhou (Author), Jia Li (Author), Yuying Yuan (Author), Yu Mo (Author), Qiang Liu (Author), Jen-Yu Tseng (Author), Diego Shih-Chieh Lin (Author), Shu-Huei Shen (Author), Yu Liu (Author), Weiping Ye (Author), Yuen Nei Cheung (Author), Ka Yiu Yuen (Author), Siyuan Lin (Author), Meili Fu (Author), Hongyun Zhang (Author), Na Liu (Author), Jian Wang (Author), Huanming Yang (Author), Yuying Wang (Author), Shen Li (Author), Shushu Fan (Author), Xin Jin (Author), Mao Mao (Author), Pi-Lin Sung (Author)
• Format: Book
• Published: Elsevier, 2018-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: The coexistence of maternal malignancy and pregnancy has received increasing attention in Noninvasive prenatal testing (NIPT) studies. Malignancy in pregnant women potentially affects the copy number variation (CNV) profile in NIPT results. Only one case of hematologic cancer has been rep...