Adaptive thermogenesis in brown adipose tissue involves activation of pannexin-1 channels

• Main Authors: Subramanian Senthivinayagam (Author), Vlad Serbulea (Author), Clint M. Upchurch (Author), Renata Polanowska-Grabowska (Author), Suresh K. Mendu (Author), Srabani Sahu (Author), Prathiba Jayaguru (Author), Kevin W. Aylor (Author), Mahendra D. Chordia (Author), Limor Steinberg (Author), Nathaniel Oberholtzer (Author), Seichii Uchiyama (Author), Noriko Inada (Author), Ulrike M. Lorenz (Author), Thurl E. Harris (Author), Susanna R. Keller (Author), Akshaya K. Meher (Author), Alexandra Kadl (Author), Bimal N. Desai (Author), Bijoy K. Kundu (Author), Norbert Leitinger (Author)
• Format: Book
• Published: Elsevier, 2021-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Brown adipose tissue (BAT) is specialized in thermogenesis. The conversion of energy into heat in brown adipocytes proceeds via stimulation of β-adrenergic receptor (βAR)-dependent signaling and activation of mitochondrial uncoupling protein 1 (UCP1). We have previously demonstrated a fun...