The Multifaceted Roles of NRF2 in Cancer: Friend or Foe?

• Main Authors: Christophe Glorieux (Author), Cinthya Enríquez (Author), Constanza González (Author), Gabriela Aguirre-Martínez (Author), Pedro Buc Calderon (Author)
• Format: Book
• Published: MDPI AG, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Physiological concentrations of reactive oxygen species (ROS) play vital roles in various normal cellular processes, whereas excessive ROS generation is central to disease pathogenesis. The nuclear factor erythroid 2-related factor 2 (NRF2) is a critical transcription factor that regulates the cellu...