Gut microbiota impairs insulin clearance in obese mice

• Main Authors: Kevin P. Foley (Author), Soumaya Zlitni (Author), Brittany M. Duggan (Author), Nicole G. Barra (Author), Fernando F. Anhê (Author), Joseph F. Cavallari (Author), Brandyn D. Henriksbo (Author), Cassandra Y. Chen (Author), Michael Huang (Author), Trevor C. Lau (Author), Roxanne Plante (Author), Michael Schwab (Author), André Marette (Author), Jonathan D. Schertzer (Author)
• Format: Book
• Published: Elsevier, 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Hyperinsulinemia can be both a cause and consequence of obesity and insulin resistance. Hyperinsulinemia can result from increased insulin secretion and/or reduced insulin clearance. While many studies have focused on mechanisms triggering insulin secretion during obesity, the triggers fo...