Adenylosuccinic Acid: An Orphan Drug with Untapped Potential

• Main Authors: Emma Rybalka (Author), Stephanie Kourakis (Author), Charles A. Bonsett (Author), Behzad Moghadaszadeh (Author), Alan H. Beggs (Author), Cara A. Timpani (Author)
• Format: Bog
• Udgivet: MDPI AG, 2023-05-01T00:00:00Z.
• Fag: article
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Adenylosuccinic acid (ASA) is an orphan drug that was once investigated for clinical application in Duchenne muscular dystrophy (DMD). Endogenous ASA participates in purine recycling and energy homeostasis but might also be crucial for averting inflammation and other forms of cellular stress during...