Pharmacological characterization of nicotine-induced tremor: Responses to anti-tremor and anti-epileptic agents

• Main Authors: Naofumi Kunisawa (Author), Saki Shimizu (Author), Masaki Kato (Author), Higor A. Iha (Author), Chihiro Iwai (Author), Mai Hashimura (Author), Mizuki Ogawa (Author), Shohei Kawaji (Author), Kazuma Kawakita (Author), Keisuke Abe (Author), Yukihiro Ohno (Author)
• Format: Book
• Published: Elsevier, 2018-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We previously showed that nicotine evoked kinetic tremor by activating the inferior olive, which is implicated in the pathogenesis of essential tremor, via α7 nicotinic acetylcholine receptors. Here, we evaluated the effects of various anti-tremor and anti-epileptic agents on nicotine-induced tremor...