Defining levels of dengue virus serotype-specific neutralizing antibodies induced by a live attenuated tetravalent dengue vaccine (TAK-003).

• Main Authors: Laura J White (Author), Ellen F Young (Author), Mark J Stoops (Author), Sandra R Henein (Author), Elizabeth C Adams (Author), Ralph S Baric (Author), Aravinda M de Silva (Author)
• פורמט: ספר
• יצא לאור: Public Library of Science (PLoS), 2021-03-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

The four dengue virus serotypes (DENV1-4) infect several hundred million people each year living in tropical and sub-tropical regions. Clinical development of DENV vaccines is difficult because immunity to a single serotype increases risk of severe disease during a second infection with a new seroty...