m6A methyltransferase METTL3 programs CD4+ T-cell activation and effector T-cell differentiation in systemic lupus erythematosus

• Main Authors: Shuang Lu (Author), Xingyu Wei (Author), Huan Zhu (Author), Zhi Hu (Author), Meiling Zheng (Author), Jiali Wu (Author), Cheng Zhao (Author), Shuang Yang (Author), Delong Feng (Author), Sujie Jia (Author), Hongjun Zhao (Author), Ming Zhao (Author)
• Format: Book
• Published: BMC, 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Systemic lupus erythematosus (SLE) is an autoimmune disorder in which excessive CD4+ T-cell activation and imbalanced effector T-cell differentiation play critical roles. Recent studies have implied a potential association between posttranscriptional N6-methyladenosine (m6A) modi...