Lower sertraline plasma concentration in patients co‐medicated with clozapine-Implications for pharmacological augmentation strategies in schizophrenia

• Main Authors: Arnim Johannes Gaebler (Author), Ekkehard Haen (Author), Nagia Ben Omar (Author), Katharina Endres (Author), Christoph Hiemke (Author), Georgios Schoretsanitis (Author), Michael Paulzen (Author)
• Format: Book
• Published: Wiley, 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Augmentation of antipsychotic treatment with antidepressants represents a common and beneficial treatment strategy in patients suffering from schizophrenia. Combining clozapine and the selective serotonin reuptake inhibitor (SSRI) sertraline represents a clinically important strategy in pat...