In silico and in vivo evaluations of fisetin and fisetin-loaded nanosuspension on monoamine oxidase inhibition in Aβ(25-35) induced dementia in mice model

• Автори: Siti Zaidathul Iman Zolkiffly (Автор), Mizaton Hazizul Hasan (Автор), Siti Azma Jusoh (Автор), Ashok Kumar Janakiraman (Автор), Sathesh Kumar Sukumaran (Автор), Noreen Husain (Автор), Yuslina Zakaria (Автор), Hanish Singh Jayasingh Chellammal (Автор)
• Формат: Книга
• Опубліковано: Elsevier, 2024-12-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Background: Amyloid beta (Aβ) plaques on the extracellular matrix and intracellular neurofibrillary tangles comprise the key indicative pathology of Alzheimer's disease (AD). Fisetin, an antioxidant bioactive compound having pharmacotherapeutic effects is applied by traditional Chinese medicine...