Design and Development of Novel Urea, Sulfonyltriurea, and Sulfonamide Derivatives as Potential Inhibitors of Sphingosine Kinase 1

Design and Development of Novel Urea, Sulfonyltriurea, and Sulfonamide Derivatives as Potential Inhibitors of Sphingosine Kinase 1

Sphingosine kinase 1 (SphK1) is one of the well-studied drug targets for cancer and inflammatory diseases. Recently discovered small-molecule inhibitors of SphK1 have been recommended in cancer therapeutics; however, selectivity and potency of first-generation inhibitors are great challenge. In sear...

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Main Authors: Sonam Roy (Author), Amarjyoti Das Mahapatra (Author), Taj Mohammad (Author), Preeti Gupta (Author), Mohamed F. Alajmi (Author), Afzal Hussain (Author), Md. Tabish Rehman (Author), Bhaskar Datta (Author), Md. Imtaiyaz Hassan (Author)
Format: Book
Published: MDPI AG, 2020-06-01T00:00:00Z.
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3rd Floor Main Library

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