Raynaud's Phenomenon: a Brief Review of the Underlying Mechanisms
Raynaud's phenomenon (RP) is characterized by exaggerated cold-induced vasoconstriction. This augmented vasoconstriction occurs by virtue of a reflex response to cooling via the sympathetic nervous system as well as by local activation of α2C adrenoceptors (α2C-AR). In a cold-initiated, mitocho...
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Frontiers Media S.A.,
2016-11-01T00:00:00Z.
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