Puerarin attenuates myocardial ischemic injury and endoplasmic reticulum stress by upregulating the Mzb1 signal pathway

• Main Authors: Jiaojiao Xue (Author), Haolin Ren (Author), Qi Zhang (Author), Jing Gu (Author), Qian Xu (Author), Jiaxi Sun (Author), Lu Zhang (Author), Ming-Sheng Zhou (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

ObjectiveThis study investigated the role of Mzb1 in puerarin protection against heart injury and dysfunction in acute myocardial infarction (AMI) mice.MethodsC57BL/6 mice were pretreated with and without puerarin at doses of 50 mg/kg and 100 mg/kg for 14 days before establishing the AMI model. An A...