Analysis of common <it>PTPN1 </it>gene variants in type 2 diabetes, obesity and associated phenotypes in the French population

• Main Authors: Marre Michel (Author), Balkau Beverley (Author), Charpentier Guillaume (Author), Bibi Amina (Author), Dechaume Aurélie (Author), Lecoeur Cécile (Author), Cheyssac Claire (Author), Froguel Philippe (Author), Gibson Fernando (Author), Vaxillaire Martine (Author)
• Format: Book
• Published: BMC, 2006-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>The protein tyrosine phosphatase-1B, a negative regulator for insulin and leptin signalling, potentially modulates glucose and energy homeostasis. PTP1B is encoded by the <it>PTPN1 </it>gene located on chromosome 20q13 sh...